Guangzhou Mandison Biotechnology Co., Ltd.  

Product Name: Quinine Dihydrochloride Injection 400mg/4ml GMP Certificated Western Medicine Pharmaceutical Technology: Chemical Synthesis Type: Biological Products Shape: Injection State: Liquid Suitable for: Elderly, Children, Adult Usage Mode: For external use Application: Internal Medicine Standard: Bp/USP Storage: Protect From Light. Packaging: 5ampoules/Box Trademark: OEM Specification: Quinine Dihydrochloride 400mg/4ml Origin: China Product Description Product name:Quinine Dihydrochloride injectionCategory:InjectionPackage:400mg/4ml*5ampoules/boxBrand:OEM/GMPPackaging Details:As usual, we also can make as your requirementDescriptionQuinine dihydrochloride injectionIngredientsThis product is asterile aqueous solution of quinine dihydrochloride.Molecular Formula: C20H24N2O2·2HClMolecular weight: 397.34IndicationsFor the treatment of cerebral malaria and other severe falciparum malaria.Dosage1. Adult dosage According to the body weight of 5~ 10mg/kg (the highest amount of 500mg), adding intravenous injection of sodium chloride injection 500ml, 4hours after the drip, 12 hours after repeated 1times, the condition improved and then changed oral.2. Pediatric Dosage The dose is the same as adults, and the body weight is 5to 10 mg/kg (the highest amount is 500 mg).Adverse reactions1. The daily dosage of this product is more than 1g or it is used for along time. It often leads to cinchona reaction. This reaction is similar to salicylic acid. It has symptoms such as tinnitus, headache, nausea, vomiting, visual hearing loss, etc. Severe person has temporary deafness and stops. After medicine can often be restored;2. When the dose is more than 4g within 24 hours, it can directly damage the nerve tissue and contract the retinal blood vessels, and the visual field is reduced, diplopia, amblyopia and so on;3. In the case of large-dose poisoning, in addition to the above-mentioned increase in the reaction, it can also inhibit the myocardium, expand peripheral blood vessels and cause sudden drop in blood pressure, slow and shallow breathing, fever, irritable dryness, sputum, etc., and more death from respiratory paralysis;4. Asmall number of patients are highly sensitive to quinine, and small amounts can cause serious cinchona reactions;5. Asmall number of patients with falciparum malaria can use asmall amount of quinine to cause acute hemolysis (black urine fever) to death;6. Quinine can also cause skin rash, itching, asthma, etc.;7. Intravenous infusion should be closely observed blood pressure changes.ContraindicationPregnant woman disabled.Precautions1. For patients with asthma, atrial fibrillation and other severe heart conditions, patients with glucose-6-phosphate dehydrogenase deficiency and menstrual periods should be used with caution.2. Interference with Diagnosis Quinine interferes with the determination of 17-hydroxysteroids.3. Intravenous injection is prone to shock, so intravenous injection is strictly forbidden.StorageProtected from light, closed.